Medication Overview
Kevzara (sarilumab) is an injectable prescription medication used primarily to treat adults with moderate to severe rheumatoid arthritis who have not responded well to one or more disease-modifying antirheumatic drugs (DMARDs). Kevzara works by blocking the interleukin-6 (IL-6) receptor, a protein that plays a significant role in the inflammatory process associated with rheumatoid arthritis.
Who Should Consider Kevzara? Kevzara is suitable for adults who:
- Have moderate to severe rheumatoid arthritis.
- Have not responded adequately to one or more DMARDs.
How is Kevzara Administered? Kevzara is administered through subcutaneous injection. Common sites for injection include the thigh, lower abdomen, or upper arms. Patients are typically instructed by healthcare professionals on how to self-administer using a pre-filled syringe or auto-injector. The typical dosing schedule involves injections every two weeks.
Important Information for Kevzara Users:
- How to Use: Follow your healthcare provider’s instructions for self-administering Kevzara injections.
- Storage: Store Kevzara in the refrigerator. Allow the medication to reach room temperature before injecting to minimize discomfort.
- Side Effects: Common side effects include injection site reactions, upper respiratory infections, and elevated liver enzymes. Report any severe or unexpected symptoms to your healthcare provider.
- Monitoring: Regular medical check-ups and possibly liver function tests are recommended to monitor the effectiveness of the treatment and to manage any side effects.
Medication Warnings
- Infections: Kevzara can compromise the immune system, increasing the risk of serious infections. Promptly report any signs of infection, such as fever, chills, or persistent cough, to your healthcare provider.
- Liver Problems: Kevzara can cause liver problems. Regular monitoring of liver function is recommended.
- Blood Cell Counts: Treatment with Kevzara may result in changes in blood cell counts. Regular blood tests are needed to monitor these levels.
- Allergic Reactions: Seek immediate medical help if you experience symptoms like rash, hives, swelling of the face, or difficulty breathing.
- Gastrointestinal Perforations: There is a risk of gastrointestinal perforations. Inform your doctor if you experience severe abdominal pain.
Who Should and Shouldn’t Take Kevzara?
- Suitable Candidates:
- Adults with moderate to severe rheumatoid arthritis who have not found relief with traditional DMARDs.
- Unsuitable Candidates:
- Individuals with active, severe infections.
- Patients with known hypersensitivity to sarilumab or any components of the formulation.
- Those with a history of severe liver disease or gastrointestinal perforation.
For more detailed information and personalized advice, consult your healthcare provider.
