Medication Overview
Simponi Aria (golimumab) is an injectable prescription medication used to treat several autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. It works by blocking tumor necrosis factor (TNF), a protein that contributes to inflammation and immune system activity.
Who Should Consider Simponi Aria? Simponi Aria is suitable for adults who:
Have moderate to severe rheumatoid arthritis
- Are diagnosed with active ankylosing spondylitis.
- Suffer from active psoriatic arthritis.
Have moderate to severe rheumatoid arthritis
How is Simponi Aria Administered?
Simponi Aria is administered as an intravenous (IV) infusion. Simponi Autoinject is available for subcutaneous injection and common sites to inject include abdomen and thighs. The injection is done every month for self administration.
Important Information for Simponi Aria Users:
- How to Use: Follow your healthcare provider’s instructions for receiving Simponi Aria infusions.
- Storage: Simponi Aria is usually handled and prepared by healthcare professionals in a medical setting.
- Side Effects: Common side effects include upper respiratory infections, headache, and elevated blood pressure. Serious side effects can include severe infections, allergic reactions, and the reactivation of hepatitis B in patients who have had the virus. Report any severe or unusual symptoms to your healthcare provider.
- Monitoring: Regular monitoring is necessary to check for side effects and to ensure the effectiveness of the treatment. This may include blood tests and assessments for signs of infection.
Medication Warnings
- Infections: Simponi Aria can weaken the immune system, significantly increasing the risk of serious infections. Report any signs of infection to your healthcare provider immediately.
- Allergic Reactions: Some patients may experience severe allergic reactions during or after the infusion. Immediate medical attention is required for symptoms such as difficulty breathing, chest pain, or swelling.
- Heart Failure: Patients with existing heart failure should be closely monitored as Simponi Aria can cause new onset or worsening of heart failure symptoms.
- Liver Injury: Rare cases of severe liver injury have been reported. Patients should report any symptoms such as jaundice, severe fatigue, or abdominal pain.
- Cancer: Long-term use of TNF blockers, including Simponi Aria, may increase the risk of lymphoma and other cancers.
Who Should and Shouldn’t Take Simponi Aria?
- Suitable Candidates:
- Individuals with certain autoimmune diseases who have not responded to standard therapies.
- Unsuitable Candidates:
- Individuals with severe, active infections.
- Patients with known hypersensitivity to golimumab or any components of the formulation.
- Those with moderate to severe heart failure or significant liver disease.
For more detailed information and personalized advice, consult your healthcare provider.
