Medication Overview
Stelara (ustekinumab) is an injectable prescription medication used to treat several immune-mediated conditions, including moderate to severe plaque psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. It works by targeting the interleukin-12 and interleukin-23 pathways, which are key drivers of the inflammatory processes in these diseases.
Who Should Consider Stelara? Stelara is suitable for adults and, in some cases, children who:
- Have moderate to severe plaque psoriasis and are candidates for phototherapy or systemic therapy.
- Suffer from active psoriatic arthritis.
- Are diagnosed with moderate to severe Crohn's disease or ulcerative colitis and have not responded adequately to conventional therapies.
How is Stelara Administered? Stelara is administered as a subcutaneous injection for psoriasis and psoriatic arthritis, and as an intravenous infusion for Crohn’s disease and ulcerative colitis. The initial doses are followed by maintenance doses typically every 8 to 12 weeks, depending on the condition being treated.
Important Information for Stelara Users:
- How to Use: Follow your healthcare provider’s instructions for receiving Stelara injections or infusions.
- Storage: Stelara is usually stored in the refrigerator and should not be frozen. It is generally prepared and administered by healthcare professionals.
- Side Effects: Common side effects include injection site reactions, upper respiratory infections, and fatigue. Serious side effects can include severe infections, allergic reactions, and potentially an increased risk of certain cancers. Report any severe or unusual symptoms to your healthcare provider.
- Monitoring: Regular monitoring is necessary to check for side effects and to ensure the effectiveness of the treatment. This may include blood tests and assessments for signs of infection.
Medication Warnings
- Infections: Stelara can weaken the immune system, significantly increasing the risk of serious infections. Report any signs of infection to your healthcare provider immediately.
- Allergic Reactions: Some patients may experience severe allergic reactions during or after the administration. Immediate medical attention is required for symptoms such as difficulty breathing, chest pain, or swelling.
- Cancer: Long-term use of Stelara may increase the risk of developing certain types of cancer. Discuss your medical history and risk factors with your doctor.
- Tuberculosis: Patients should be tested for tuberculosis before starting treatment with Stelara.
Who Should and Shouldn’t Take Stelara?
- Suitable Candidates:
- Individuals with specific immune-mediated conditions who require targeted intervention after other treatments have failed.
- Unsuitable Candidates:
- Individuals with severe, active infections.
- Patients with known hypersensitivity to ustekinumab or any components of the formulation.
- Those with a history of tuberculosis unless the infection is fully treated.
For more detailed information and personalized advice, consult your healthcare provider.
