Medication Overview
Cimzia (certolizumab pegol) is an injectable prescription medicine designed to treat various autoimmune diseases, including rheumatoid arthritis, Crohn’s disease, psoriatic arthritis, ankylosing spondylitis, and plaque psoriasis. It operates by inhibiting tumor necrosis factor (TNF), a substance that drives inflammation in autoimmune conditions.
Who Should Consider Cimzia? Cimzia is suitable for adults who:
- Have moderate to severe rheumatoid arthritis.
- Suffer from Crohn's disease and have not adequately responded to other treatments.
- Are diagnosed with active psoriatic arthritis or ankylosing spondylitis.
- Require treatment for moderate to severe plaque psoriasis.
How is Cimzia Administered?
Cimzia is given as a subcutaneous injection in either the abdomen or thigh. Your healthcare provider will demonstrate how to use the pre-filled syringe or auto-injector. The dosing schedule varies depending on the condition treated and the specific regimen prescribed by your healthcare provider.
Important Information for Cimzia Users:
- How to Use: Adhere to your healthcare provider’s instructions for injecting Cimzia.
- Storage: Store Cimzia in the refrigerator. Allow it to reach room temperature before use.
- Side Effects: Common side effects include upper respiratory infections, rash, urinary tract infections, and injection site reactions. Report any severe or unusual symptoms to your doctor.
- Monitoring: Regular medical check-ups and blood tests are necessary to monitor your health and the medication’s effectiveness.
Medication Warnings
- Infections: Cimzia may compromise your immune system, elevating the risk of serious infections. Report any signs of infection, such as fever, chills, or persistent cough, to your doctor immediately.
- Cancer Risk: There is a potential increased risk of certain cancers, including lymphoma. Discuss your medical history and risk factors with your doctor.
- Allergic Reactions: Seek immediate medical help if you experience symptoms like rash, itching, swelling, dizziness, or trouble breathing.
- Heart Failure: Cimzia may cause or exacerbate heart failure. Inform your healthcare provider if you experience symptoms such as shortness of breath, ankle or feet swelling, or sudden weight gain.
- Nervous System Problems: There is a risk of nervous system issues, such as multiple sclerosis and seizures. Inform your doctor if you have a history of these conditions or if you experience new symptoms.
Who Should and Shouldn’t Take Cimzia?
- Suitable Candidates:
- Adults with specified autoimmune diseases requiring TNF inhibition.
- Unsuitable Candidates:
- Individuals with severe, active infections.
- Patients with known hypersensitivity to certolizumab pegol or any component of the product.
- Those with severe heart failure or pre-existing severe nervous system disorders, unless assessed and monitored closely by a healthcare professional.
