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Medication Overview

Wegovy (semaglutide) is an injectable prescription medication used for chronic weight management in adults and adolescents. It is indicated for individuals with a body mass index (BMI) of 30 or greater (obesity), or a BMI of 27 or greater (overweight) with at least one weight-related medical condition, such as high blood pressure, type 2 diabetes, or high cholesterol.

Who should consider Wegovy?

Wegovy is suitable for adults and children who:

  • Have a BMI of 30 or greater (obesity).
  • Have a BMI of 27 or greater and also suffer from at least one weight-related condition, such as hypertension, type 2 diabetes, or high cholesterol.
  • Require long-term weight management and have not achieved sustainable weight loss with diet and exercise alone.

How is Wegovy Administered?

Wegovy is administered as a subcutaneous injection. It is typically injected once a week, and the injection sites can include the abdomen, thigh, or upper arm. Patients are trained by healthcare professionals on how to self-administer the medication using a pre-filled, single-dose pen injector. The dose starts low and gradually increases over 16-20 weeks to reduce the risk of gastrointestinal side effects.

Important Information for Wegovy Users

  • How to Use: Inject Wegovy once weekly on the same day each week. Follow your healthcare provider’s specific instructions.
  • Storage: Keep Wegovy in the refrigerator but avoid freezing. Allow it to come to room temperature before injecting.
  • Side Effects: Common side effects include nausea, vomiting, diarrhea, constipation, and stomach pain. If you experience severe side effects such as signs of a thyroid tumor (e.g., a lump in the neck), contact your healthcare provider immediately.
  • Monitoring: Regular check-ups are advised to monitor the effectiveness of Wegovy and manage any potential side effects.

Medication Warnings

  • Thyroid Cancer Risk: Wegovy may increase the risk of thyroid tumors, including medullary thyroid carcinoma (MTC). Do not use Wegovy if you or your family have a history of MTC or multiple endocrine neoplasia syndrome type 2 (MEN 2).
  • Pancreatitis: Inform your doctor if you experience severe stomach pain, which could be a sign of pancreatitis.
  • Gallbladder Problems: Wegovy can cause gallbladder-related issues, such as gallstones. Report any symptoms like intense stomach pain or yellowing of the skin (jaundice).
  • Low Blood Sugar: Especially in those with type 2 diabetes taking other glucose-lowering medications, Wegovy may cause low blood sugar (hypoglycemia). Monitor your blood sugar levels closely.
  • Pregnancy and Breastfeeding: Do not use Wegovy during pregnancy, as weight loss during pregnancy can harm the baby. Discuss any plans to become pregnant with your healthcare provider.

Who Should and Shouldn’t Take Wegovy?

Suitable Candidates:

  • Adults and adolescents with obesity (BMI ≥30) or overweight (BMI ≥27) who also have weight-related conditions.
  • Individuals seeking long-term weight management and lifestyle changes.

Unsuitable Candidates:

  • Individuals with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2).
  • Those with a history of severe allergic reactions to semaglutide or any of the components in Wegovy.
  • Pregnant women or those planning to become pregnant.

For more detailed information and personalized advice, consult your healthcare provider.