Medications
Explore treatments, side effects, and preventive care for STDs, women’s health, and neurological conditions.
Saphnelo Treatment
Saphnelo (anifrolumab) is a monoclonal antibody used to treat systemic lupus erythematosus (SLE) in adults with moderate to severe disease. It works by targeting the type I interferon receptor, a key driver of inflammation and immune system overactivity in lupus, helping to reduce disease activity and prevent organ damage.
Common symptoms of SLE include persistent fatigue, joint pain and swelling, skin rashes (often a butterfly-shaped rash across the cheeks and nose), sensitivity to sunlight, unexplained fever, chest pain, kidney inflammation, and hair loss.
SLE is primarily caused by a combination of genetic predisposition, environmental triggers (e.g., sunlight exposure, infections, certain medications), and hormonal factors (e.g., estrogen levels). These factors can lead to an overactive immune system that mistakenly attacks healthy tissues.
Diagnosis involves a thorough medical history and a combination of tests, including blood tests (e.g., ANA, anti-dsDNA, complement levels), urine tests (to check for kidney damage), and imaging studies (e.g., chest X-rays, echocardiograms) to assess organ involvement.
Saphnelo is administered via intravenous infusion every four weeks. It is typically combined with standard lupus therapies such as corticosteroids, immunosuppressants, and antimalarial drugs like hydroxychloroquine to reduce inflammation and prevent flares.
Doctors commonly prescribe Saphnelo, hydroxychloroquine, methotrexate, corticosteroids (e.g., prednisone), and other immunosuppressive medications such as mycophenolate mofetil or azathioprine.
Supportive measures include a balanced diet rich in fruits, vegetables, and lean protein, adequate hydration, sun protection (e.g., sunscreen, protective clothing), regular but gentle exercise, stress management techniques (e.g., yoga, meditation), and sufficient rest to reduce fatigue.
Long-term management involves regular follow-up visits with a rheumatologist, routine blood and urine tests, monitoring organ function, adhering to prescribed medications, and managing side effects. Emotional support through counseling or support groups can also improve quality of life.
While lupus cannot be prevented, avoiding known triggers such as excessive sun exposure, infections, and stress, along with adhering to prescribed treatments and maintaining a healthy lifestyle, can help minimize flare-ups and complications.
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