Medication Overview
Olumiant (baricitinib) is an oral medication approved for the treatment of adults with moderate to severe rheumatoid arthritis who have not responded adequately to one or more tumor necrosis factor (TNF) inhibitors. It belongs to a class of medications known as Janus kinase (JAK) inhibitors, which work by blocking the activity of enzymes involved in the inflammatory process that contributes to the symptoms of rheumatoid arthritis.
Who Should Consider Olumiant? Olumiant is suitable for adults who:
- Have moderate to severe rheumatoid arthritis.
- Have not responded adequately to one or more TNF inhibitors.
How is Olumiant Administered?
Olumiant is taken orally, typically once a day. The tablet should be swallowed whole with water, with or without food.
Important Information for Olumiant Users:
- How to Use: Follow your healthcare provider’s dosage instructions carefully.
- Storage: Store Olumiant at room temperature, away from moisture and heat.
- Side Effects: Common side effects include upper respiratory tract infections, nausea, elevated liver enzymes, and high blood pressure. Report any severe or unexpected symptoms to your healthcare provider.
- Monitoring: Regular medical check-ups and possibly blood tests are recommended to monitor your health and the medication’s effectiveness, especially liver function and blood cell counts.
Medication Warnings
- Infections: Olumiant can compromise the immune system, increasing the risk of serious infections. Promptly report any signs of infection, such as fever, chills, or persistent cough, to your healthcare provider.
- Blood Clots: There is an increased risk of blood clots, which can be serious and lead to death. Watch for symptoms of thrombosis such as swelling, pain, or redness in the limbs.
- Liver Problems: Olumiant can cause liver problems. Regular monitoring of liver function is recommended.
- Cancer: JAK inhibitors, including Olumiant, may increase the risk of certain cancers. Discuss your cancer risk with your doctor.
- Cholesterol Levels: Treatment with Olumiant may affect your cholesterol levels. Blood tests to monitor these levels should be conducted regularly.
Who Should and Shouldn’t Take Olumiant?
- Suitable Candidates:
- Adults with moderate to severe rheumatoid arthritis who have not found relief with TNF inhibitors.
- Unsuitable Candidates:
- Individuals with active, severe infections.
- Patients with known hypersensitivity to baricitinib or any components of the formulation.
- Those at increased risk for blood clots or with a history of liver disease.
For more detailed information and personalized advice, consult your healthcare provider.