Enbrel (etanercept) is an injectable prescription medication widely used to treat several autoimmune conditions, including moderate to severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and plaque psoriasis. It functions by inhibiting tumor necrosis factor (TNF), a protein in the body that causes inflammation and contributes to the symptoms of these autoimmune diseases.

Who Should Consider Enbrel? Enbrel is suitable for adults and, in some cases, children who:

  • Have moderate to severe rheumatoid arthritis.
  • Suffer from psoriatic arthritis.
  • Are diagnosed with ankylosing spondylitis.
  • Require treatment for chronic moderate to severe plaque psoriasis.
  • Children with juvenile idiopathic arthritis.

How is Enbrel Administered? Enbrel is administered through subcutaneous injection. Common sites for injection include the thigh, lower abdomen, or upper arms. Patients are usually instructed by healthcare professionals on how to self-administer using a pre-filled syringe or auto-injector. The dosing frequency typically includes weekly injections.

Important Information for Enbrel Users:

  • How to Use: Follow the healthcare provider’s instructions for self-administering Enbrel injections.
  • Storage: Store Enbrel in the refrigerator. Allow the medication to reach room temperature before injecting to minimize discomfort.
  • Side Effects: Common side effects include injection site reactions, upper respiratory infections, and headache. Report any severe or unexpected symptoms to your healthcare provider.
  • Monitoring: Regular medical check-ups and possibly blood tests are recommended to monitor the effectiveness of the treatment and to manage any side effects.

Medication Warnings

  • Infections: Enbrel can compromise the immune system, increasing the risk of serious infections. Promptly report any signs of infection, such as fever, chills, or persistent cough, to your healthcare provider.
  • Allergic Reactions: Seek immediate medical help if you experience symptoms like rash, hives, swelling of the face, or difficulty breathing.
  • Neurological Problems: Rarely, Enbrel can cause neurological problems, including multiple sclerosis, seizures, and optic neuritis. Discuss any personal or family history of neurological disorders with your doctor.
  • Heart Failure: Etanercept may worsen or cause new onset of heart failure. Notify your healthcare provider if you develop symptoms like shortness of breath or swelling of the ankles.

Who Should and Shouldn’t Take Enbrel?

  • Suitable Candidates:
    • Individuals diagnosed with specific autoimmune diseases requiring TNF inhibition.
    • Patients who have not responded adequately to standard therapies.
  • Unsuitable Candidates:
    • Individuals with active, severe infections.
    • Patients with known hypersensitivity to etanercept or any components of the formulation.
    • Those with a history of heart failure or significant neurological disorders, unless closely monitored by a healthcare provider.

For more comprehensive information and personalized advice, consult your healthcare provider.